Children that suffer from the chronic illness of type 1
diabetes mellitus have a diminished bone marrow density because of insulin
deficiency. Maggio et al. (2011) note
that their research attempts to look at the dose and type of exercise needed for
a child with type 1 diabetes mellitus (T1DM) that will optimize bone mineral acquisition
because research in this area is still not well defined. Thus, the main aim of
their study determines what the effects of weight-bearing physical activity on
bone mineral mass and bone turnover markers in young children with type 1
diabetes mellitus in comparison to those of healthy children.
Twenty-seven chidren who were diabetic were recruited from
the Unit of Pediatric Endocrinology and Diabetology of the University Hospitals
of Geneva between the ages of 8-12.
Thirty-two healthy children, also between the ages of 8-12 were recruited as
peers of the diabetic children or from local schools. Both the diabetic and
healthy candidates for this study were excluded for the following reasons:
presence of other chronic disease, medications, hormones other than insulin or
calcium preparations, presence of nephropathy, systematic disease or
hospitlization for more than 2 weeks in the preceding year, and participation
in competition sport (Maggio et al., 2011).
Participants with T1DM and healthy participants were randomized by gender to groups: the exercise diabetic group and the exercise healthy group (experimental groups) and the control diabetic group and the control healthy group. Maggio et al. (2011) note that this randomization process resulted in a similar girls/boys ratio within each group. Children (healthy and diabetic) who were in the exercise group were instructed to go to two 90-minute exercise sessions per week for the period of 9 months. Maggio et al. (2011) demonstrate that the exercise sessions were supervised by two physical education teachers as well as, a pediatrician with experience in T1DM. Participants took part in various weight-bearing activities such as jump rope, jumping, and gymnastics. Maggio et al. (2011) also increased intensity and difficulty levels as the months progressed. The researchers (2011) also accounted for physical leisure activity for the past 12 months via questionnaire.
Participants with T1DM and healthy participants were randomized by gender to groups: the exercise diabetic group and the exercise healthy group (experimental groups) and the control diabetic group and the control healthy group. Maggio et al. (2011) note that this randomization process resulted in a similar girls/boys ratio within each group. Children (healthy and diabetic) who were in the exercise group were instructed to go to two 90-minute exercise sessions per week for the period of 9 months. Maggio et al. (2011) demonstrate that the exercise sessions were supervised by two physical education teachers as well as, a pediatrician with experience in T1DM. Participants took part in various weight-bearing activities such as jump rope, jumping, and gymnastics. Maggio et al. (2011) also increased intensity and difficulty levels as the months progressed. The researchers (2011) also accounted for physical leisure activity for the past 12 months via questionnaire.
All the young children that participated were tested at
baseline, prior to the study, and after the 9 months had elasped during the
same period (Maggio et al., 2011). This
was done to reduce some extraneous variables such as leisure time for physical
activity and vitamin D concentrations. Body weight, height, body mass index
(BMI), pubertal development, and lead body mass were all measured. Maggio et
al. (2011) also, assessed areal bone mineral density (aBMD), lumbar spine,
right femoral nech and greater trochanter.
As for the main results, researchers (2011) found that T1DM
children that were in the exercise group (180 minutes of weight bearing
activity/week) had improved their total body and lumbar spine bone mineral
densities compared to those diabetic
patients within the control group. What
Maggio et al. (2011) find interesting is that total body and lumbar spine bone
mineral densities were improved in healthy children as much as they were in
participants with T1DM. Researchers (2011) also found that physical activity
has different influences on different bone sites in regards to gender and
pubertal stages. There are factors such as type of exercise, training duration
and volume that physical activity is dependent on, as well.
What is limiting in Maggio et al. (2011) study is that their
sample size was relatively small, therefore, generalizations towards the public
in regards to the findings can not be made with complete assurance. Researchers
(2011) further note that due to the small sample size, a sub-analysis cannot be conducted to
evaluate other factors (age and puberty) on the different variables.
This study is, however, interesting because of the quality of
the researcher’s (2011) study design and the fact that there were no drop outs
from the study. Also, researchers (2011) looked at something that still needed
defining, which will yield an additional amount of research conducted in this
area.
These findings suggest that there are positive effects of
weight-bearing physical activity on total body and lumbar spine bone mineral
aquistion with T1DM.Therefore, the take home message of this study conducted by
Maggio et al. (2011) is that weight-bearing sports (ball games, jumping
activities, gymnastics) should be encouraged and become prevalent in children
with Type 1 Diabetes Mellitus in so that bone mineral acquisition is optimized
during growth. Maggio et al. (2011) also make note that physical activity
within these diabetic patients will prevent the development of osteoporosis
later in life.
References
Maggio, Albane B., Laetitia M. Marchand, Serge Ferrari, René Rizzoli, Maurice Beghetti, and Nathalie J. Farpour-Lambert. "Physical Activity Increases Bone Mineral Density In Children With Type 1 Diabetes: A Randomized Controlled Trial." Medicine & Science in Sports & Exercise 41.Supplement 1 (2011). PubMed. Web. 17 Mar. 2012.